Name Wasterlain, Claude G.
Position Title Professor of Neurology

Research and Professional Experience.

• Instructor, Department of Neurology, Cornell University Medical College, New York, NY,1969-70.
  
• Assistant Professor of Neurology, Cornell University Medical College, New York, NY, 1970-75.
  
• Associate Professor of Neurology, Cornell University Medical College, New York, NY, 1975-76.
  
• Associate Professor of Neurology, University of California School of Medicine, Los Angeles, CA 1976-79.
  
• Vice-Chair, Department of Neurology, University of California School of Medicine, Los Angeles, CA , 1976-present.
  
• Professor of Neurology, University of California School of Medicine, Los Angeles, CA 1979- present.
  
• Chief, Neurology Section, VA Medical Center, Sepulveda, CA 1976-79.
  
• Chief, Neurology Service, VA Medical Center, Sepulveda, CA 1979-98.
  
• Chair, Department of Neurology, VA Greater Los Angeles Healthcare System, 1998-present.
  
  

Honors and Awards:

• M.D. with Distinction.
  
• L.Sc. Summa Cum Laude.
  
• Fullbright Fellowship, 1963 (declined).
  
• Award for Research of the New York Neurological Society ("young investigator" award), 1965.
  
• Bertha Spiva Memorial Fellowship of the National Multiple Sclerosis Society, 1968-1969.
  
• Research Career Development Award, NIH, 1973-1976.
  
• Elected "Outstanding Faculty Member" (best clinical teacher) by the UCLA-SFVMP Interns and Residents Association, 1976-77.
  
• Grass Traveling Fellow, 1983.
  
• William Evans Fellow, Auckland Medical School, 1984.
  
• Visiting Professor, University of Otago, 1984.
  
• American Epilepsy Society-Milken Family Foundation Award for Basic Research in Epilepsy,  1992.
  
• Distinguished Lecturer in Neuroscience, LSU Center of Excellence, 1996.
  
• "Golden Hammer" teaching award, UCLA, 1996.
  
  

Recent Professional Publications.  (Total: 490)

• Saar K, Mazarati AM, Mahlapuu R, Hallnemo G, Soomets U, Kilk K, Hellberg S, Pooga M, Tolf BR, Shi TS, Hokfelt T, Wasterlain C, Bartfai T, Langel U. Anticonvulsant activity of a nonpeptide galanin agonist. Proc. Natl Acad. Sci. (USA) ) 99: 7136-7141, 2002
  
• Mazarati AM, Sofia D, Wasterlain CG. Anticonvulsant and antiepileptogenic effects of fluorofelbamate in experimental status epilepticus. Seizure, in press.
  
• Tan Z, Sankar R, Shin D, Sun N, Liu H, Wasterlain CG, Schreiber SS. Differential induction of p53 in immature and adult rat brain following lithium-pilocarpine status epilepticus. Brain Res. 2002;928:187-93.
  
• Tan Z, Sankar R, Tu W, Shin D, Liu H, Wasterlain CG, Schreiber SS. Immunohistochemical study of p53-associated proteins in rat brain following lithium-pilocarpine status epilepticus. Brain Res. 2002;929:129-38.
  
• Wasterlain, CG, Niquet J, Liu H, Sankar R, Mazarati AM, Suchomelova L, Katsumori H, Shirasaka Y. Seizure-induced neuronal death in the immature brain. Prog. Brain Res., in press.
  
• Sankar R, Shin D, Wasterlain CG., Mazarati A., Epileptogenesis during development: injury, circuit recruitment, and plasticity. Epilepsia,43 (Suppl. 5): 47-53, 2002.
  
• Wasterlain, C.G., A. M. Mazarati, H. Liu, Niquet J, Suchomelova L, Naylor D, U Langel, R. Sankar,  Short-term plasticity of hippocampal neuropeptides in status epilepticus. Epilepsia, 43 (Suppl. 5): 20-29, 2002.
  
• Mazarati AM, Bragin A, Baldwin R, Shin D,  Wilson C, Sankar R, Naylor D, Engel JJr, Wasterlain CG, Epileptogenesis after self-sustaining status epilepticus. Epilepsia, , 43 (Suppl. 5): 74-80, 2002.
  
• Thompson KW, Wasterlain CG. Urethane anesthesia produces selective damage in the piriform cortex of the developing brain.  Brain Res Dev Brain Res. 2001;130:167-71.
  
• Liebeskind DS, Ostrzega N, Wasterlain CG, Buttner EA. Neurologic manifestations of disseminated infection with Mycobacterium abscessus.  Neurology. 2001 Mar 27;56(6):810-3.
  
• Liu H, Sankar R, Shin DH, Mazarati AM, Wasterlain CG, Patterns of status epilepticus-induced substance P expression during development. Neuroscience. 2000;101(2):297-304
  
• Sankar R, Shin D, Mazarati AM, Liu H, Katsumori H, Lezama R, Wasterlain CG, Epileptogenesis after status epilepticus reflects age- and model-dependent plasticity. Ann Neurol. 2000;48(4):580-9
  
• .            Wasterlain, C.G., Liu H., Mazarati A.M., Baldwin R.A., Shirasaka Y., Katsumori H., Thompson K.W., Sankar R., Pereira A. and Nehlig A. Self-sustaining status epilepticus: a condition maintained by potentiation of glutamate receptors and by plastic changes in substance P and other peptides neuromodulators. Epilepsia 41: S6: 134-43, 2000.
  
• Mazarati A.M., Hohmann J.G., Bacon A., Liu H., Sankar R., Steiner R.A., Wynick D.,Wasterlain C.G. Modulation of hippocampal excitability and seizures by galanin. J. Neurosci. 20:6276-6281, 2000.
  
• Sankar R, Shin D, Liu H, Katsumori H, Wasterlain CG. Granule cell neurogenesis after status epilepticus in the immature rat brain. Epilepsia. 2000;41 Suppl 6:S53-6.
  
• Rogawski MA, Wasterlain CG, Mazarati AM Mazarati et al. "...clinically available [antiepileptic drug] with a moderate affinity for the glycine site of the N-methyl-D-aspartate (NMDA) receptor". Epilepsia. 41(7):918-9, 2000.
  
• Wasterlain, C.G. and Estrada, G.. Epilepsia Partialis Continua. In: Emedicine, electronic textbook (www.Emedicine.com).  N. De Lorenzo, ed., 2000
  
• Liu, H.,  Cao Y., Basbaum A.I., Mazarati, A.M.,  Sankar, R., Wasterlain, C.G.  Resistance to excitotoxin-induced seizures and neuronal death in mice lacking the preprotachykinin A gene. .  Proc Natl Acad Sci 96:12096-12101, 1999.
  
• Liu, H., Mazarati, A.M., Katsumori, H., Sankar, R., Wasterlain, C.G.  Substance P is expressed in hippocampal principal neurons during status epilepticus and plays a critical role in the maintenance of status epilepticus.  Proc Natl Acad Sci 96:5286-5291, 1999
  
• Theodore W., Wasterlain, C.G.  Do early seizures beget epilepsy? Neurology 22:53(5):898-899, 1999.
  
• Sankar, R., Wasterlain, C.G.  Is the devil we know the lesser of two evils? Vigabatrin and visual fields.  Neurology, 52:1537-1538, 1999.
  
• Sankar, R, Shin, D, Mazarati, A.M., Liu, H., Wasterlain, C.G.  Ontogeny of self-sustaining status epilepticus.  Dev Neurosci 21:345-351, 1999.
  
• Pereira de Vasconcelos A., Mazarati, AM, Wasterlain, CG., Nehlig, A.  Self-sustaining status epilepticus after a brief electrical stimulation of the perforant path: a 2-deoxyglucose study.  Brain Res 838:110-118, 1999.
  
• Katsumori, H., Baldwin, R.A., Wasterlain, C.G.  Reverse transport of glutamate during depolarization in immature hippocampal slices.  Brain Research 819:160-164, 1999.
  
• Mazarati, A.M., Liu, H., Wasterlain, C.G.  Opioid peptide pharmacology and immunocytochemistry in an animal model of self-sustaining status epilepticus.  Neuroscience 89:167-173, 1999.
  
• Mazarati, A.M., Wasterlain, C.G.  N-methyl-D-asparate receptor antagonists abolish the maintenance phase of self-sustaining status epilepticus in rat.  Neuroscience Letters 265:187-190, 1999.
  
• Stern, John M. and Wasterlain, Claude.  Stroke.  In: Encyclopedia of Neuroscience, 2nd Edition, George Adleman, Barry Smith, eds, Elsevier Science Publishers, HR, Amsterdam, pp 1959-1961, 1999.
  
• Chen, John and Wasterlain, Claude. Ischemia. .  In: Encyclopedia of Neuroscience, 2nd Edition,  George Adleman, Barry Smith, eds, Elsevier Science Publishers, HR, Amsterdam, pp 988-991, 1999.
  
• Wasterlain, C. G.  Hippocampal lesions and lesional epilepsies: a Hebbian theory of epileptogenesis. In: Delgado-Escueta, A.V., Wilson, W., Olsen, R., Porter, R.J. (Eds) Jasper's Basic Mechanisms of the Epilepsies.  Lipincott-Raven, Philadelphia, pp 829-844, 1999.
  
• Wasterlain, CG, Thompson, K.W., Kornblum H., .Mazarati, A.M., Shirasaka, Y, Katsumori H., Liu H., and Sankar, R., Long-term effects of recurrent seizures on the developing brain. In: Childhood epilepsies and brain development, Eds A. Nehlig, J. Motte, S.L. Moshe, P. Plouin; John Libbey, London, 1999, pp 237-254.
  
• Sankar, R., Shin, D.H., Liu, H., Mazarati, A., de Vasconcelos, A. P., Wasterlain, C.G.  Patterns  of Status Epilepticus-induced neuronal injury during development and long-term consequences.  J. Neurosci 18:8382-8393, 1998.
  
• Mazarati, A.M., Liu, H., Soomets, U., Sankar, R., Shin, D., Katsumori, H., Langel, U., Wasterlain, C.G.  Galanin modulation of seizures and seizure modulation of hippocampal galanin in an animal model of status epilepticus.  J. Neurosci 18:10070-10077, 1998